Description

Enkephalin-Leu, Ala(2)-Cystamine-Dimer- CAS NO 99043-48-8 is a specialized, high-purity synthetic peptide dimer linked via a cystamine bridge, designed for advanced biochemical and pharmaceutical research. This compound is of significant interest for its role in studying opioid receptor interactions, peptide stability, and targeted drug delivery mechanisms. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in neuropharmacology, peptide therapeutics, and molecular probe development.

Application

• Biochemical Research: Used as a reference standard and active compound in studies of enkephalinergic systems and opioid peptide metabolism.
• Pharmaceutical R&D: Serves as a key intermediate or model compound in the development of novel peptide-based analgesics and CNS-targeting therapeutics.
• Drug Delivery Studies: The cystamine dimer structure makes it valuable for investigating disulfide bridge formation, stability, and controlled release mechanisms in prodrug design.
• Receptor Binding Assays: Employed in competitive binding studies to characterize affinity and selectivity for delta and mu opioid receptors.
• Protease Stability Testing: Acts as a substrate to evaluate the stability of peptide linkages against various enzymatic degradations.
• Molecular Biology: Can be used in the synthesis of peptide conjugates for labeling, imaging, or affinity purification applications.

Basic Information

Product Name	Enkephalin-Leu, Ala(2)-Cystamine-Dimer- CAS NO 99043-48-8
CAS No.	99043-48-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Leu-Enkephalin, Ala(2)-Cystamine Dimer; [Leu5]Enkephalin, [Ala2]-Cystamine Dimer; Cystamine-bridged [Ala2, Leu5]Enkephalin Dimer; H-Tyr-Ala-Gly-Phe-Leu-Cystamine-Dimer; Opioid Peptide Dimer; CAS 99043-48-8
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of Enkephalin-Leu, Ala(2)-Cystamine-Dimer is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as purity (by HPLC), peptide content, and related substances are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Solubility	Soluble in DMSO, Acetic Acid; Sparingly soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.