Description

H-Thr-Val-Oh CAS NO 99032-17-4 is a high-purity dipeptide derivative, specifically the protected form of the Threonine-Valine sequence. This compound serves as a critical building block in solid-phase peptide synthesis (SPPS), enabling the precise construction of complex peptides and proteins. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors developing novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: Key raw material for the synthesis of therapeutic peptides targeting metabolic disorders, oncology, and cardiovascular diseases.
• Biochemical Research: Used as a protected amino acid sequence in academic and industrial research for studying protein structure, function, and interactions.
• Peptide Library Construction: Essential component in combinatorial chemistry for generating diverse peptide libraries used in drug discovery and high-throughput screening.
• Cosmetic Peptide Synthesis: Building block for creating bioactive peptides used in advanced skincare formulations for anti-aging and skin repair.
• Enzyme Substrate Analog: Employed in the development of specific enzyme inhibitors and probes for diagnostic assays.

Basic Information

Product Name	H-Thr-Val-Oh
CAS No.	99032-17-4
Molecular Formula	C9H18N2O4
Molecular Weight	218.25 g/mol
Synonyms	H-Thr-Val-OH; L-Threonyl-L-valine; Thr-Val; T-V; (2S,3S)-2-[[(2S)-2-Amino-3-methylbutanoyl]amino]-3-hydroxybutanoic acid; L-Thr-L-Val; Threonine-Valine dipeptide; N-(tert-Butoxycarbonyl)-L-threonyl-L-valine (related protected form)
EINECS	Contact for details

Quality Control

Our H-Thr-Val-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation by IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and cGMP-grade standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	-15° to -25° (c=1 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.