Description

Atrial Natriuretic Factor (1-11) CAS NO 98897-21-3 is a specific, bioactive peptide fragment derived from the N-terminal region of the atrial natriuretic peptide (ANP) hormone. This compound is of significant value for cardiovascular and renal research, serving as a critical tool for studying hormone-receptor interactions, signal transduction pathways, and the physiological regulation of blood pressure and electrolyte balance. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in peptide chemistry, endocrinology, and drug discovery programs.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of natriuretic peptide receptors (NPR-A, NPR-C) and their downstream signaling mechanisms.
• Pharmacological Studies: Employed in in vitro and ex vivo assays to investigate vasodilation, diuresis, natriuresis, and the inhibition of the renin-angiotensin-aldosterone system (RAAS).
• Structure-Activity Relationship (SAR) Analysis: Serves as a key fragment for mapping the bioactive regions of the full-length ANP hormone and designing novel peptide analogs or mimetics.
• Diagnostic Development: Potential use in the development of immunoassays or biosensors for detecting ANP-related peptides in biological samples.
• Cell Culture & Molecular Biology: Applied in cell-based models to study the effects of ANP fragments on gene expression, cell proliferation, and hypertrophy in cardiac and renal tissues.

Basic Information

Product Name	Atrial Natriuretic Factor (1-11)
CAS No.	98897-21-3
Molecular Formula	C53H85N17O16S2
Molecular Weight	1240.48 g/mol
Synonyms	ANF (1-11); Atrial Natriuretic Peptide (1-11); ANP (1-11); Cardionatrin (1-11); Atriopeptin (1-11); Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg; SLRRSSCFGGR; H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH
EINECS	Contact for details

Quality Control

Our Atrial Natriuretic Factor (1-11) is produced and controlled under stringent conditions suitable for research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes batch-specific data on purity, content, and related substances. Our quality system ensures traceability and consistency, meeting the exacting standards required for reliable scientific research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%
Amino Acid Analysis	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.