Description

(Hydroxymethyl)Methylcarbamic Acid 7-Chloro-2,3-Dihydro-1-Methyl-2-Oxo-5-Phenyl-1H-1,4-Benzodiazepin-3-Yl Ester is a high-purity chemical intermediate of significant importance in advanced pharmaceutical synthesis. This compound is valued for its role as a key building block in the development of active pharmaceutical ingredients (APIs), particularly within the benzodiazepine class. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and production of specialized therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel benzodiazepine-based Active Pharmaceutical Ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new therapeutic candidates.
• Process Chemistry: Serves as a key building block in the scale-up and optimization of synthetic routes for target molecules.
• Reference Standard: Employed as an analytical standard for quality control and method validation in pharmaceutical analysis.
• Custom Synthesis: A starting material for the contract manufacturing of complex, high-value specialty chemicals.

Basic Information

Product Name	(Hydroxymethyl)Methylcarbamic Acid 7-Chloro-2,3-Dihydro-1-Methyl-2-Oxo-5-Phenyl-1H-1,4-Benzodiazepin-3-Yl Ester
CAS No.	98847-55-3
Molecular Formula	C19H18ClN3O4
Molecular Weight	387.82 g/mol
Synonyms	7-Chloro-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl N-(hydroxymethyl)-N-methylcarbamate; 3-[(Hydroxymethyl)(methyl)carbamoyl]oxy-7-chloro-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; Lormetazepam Impurity; Lormetazepam Related Compound; Lormetazepam Intermediate; 1,4-Benzodiazepin-2-one derivative
EINECS	Contact for details

Quality Control

Our (Hydroxymethyl)Methylcarbamic Acid 7-Chloro-2,3-Dihydro-1-Methyl-2-Oxo-5-Phenyl-1H-1,4-Benzodiazepin-3-Yl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards suitable for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.