Description

5-Ethyl-1-(3-Hydroxy-4-(Hydroxymethyl)Cyclopentyl)-2,4(1H,3H)-Pyrimidinedione is a high-purity nucleoside analog intermediate of significant interest in advanced pharmaceutical synthesis. This compound matters for its role as a critical building block in the development of novel antiviral and anticancer therapeutics, where precise molecular structure is paramount. Pharmaceutical R&D laboratories and fine chemical manufacturers require this material for its specific stereochemistry and functional groups, which are essential for creating targeted active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of nucleoside-based antiviral drugs.
• Antiviral Drug Research: Used in the R&D of novel therapeutic agents targeting viral polymerases and replication mechanisms.
• Oncology Research: Serves as a building block for experimental chemotherapeutic compounds that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Probe Development: Utilized in creating labeled or modified nucleosides for studying enzymatic processes and metabolic pathways.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for constructing complex, chiral molecular architectures.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the cGMP production of clinical trial materials and commercial APIs.

Basic Information

Product Name	5-Ethyl-1-(3-Hydroxy-4-(Hydroxymethyl)Cyclopentyl)-2,4(1H,3H)-Pyrimidinedione
CAS No.	98736-93-7
Molecular Formula	C12H16N2O4
Molecular Weight	252.27 g/mol
Synonyms	5-Ethyl-1-[3-hydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidine-2,4(1H,3H)-dione; 5-Ethyl-1-(3-hydroxy-4-hydroxymethylcyclopentyl)uracil; Cyclopentyl Pyrimidinedione Derivative; Nucleoside Analog Intermediate; 98736-93-7; 5-Ethyl-1-(3-hydroxy-4-(hydroxymethyl)cyclopentyl)uracil
EINECS	Contact for details

Quality Control

Our 5-Ethyl-1-(3-Hydroxy-4-(Hydroxymethyl)Cyclopentyl)-2,4(1H,3H)-Pyrimidinedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect the material from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.