Description

n-(2,4-Difluorophenyl)-2,2,2-Trifluoroacetamide is a high-purity fluorinated acetamide derivative, a key building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both difluorophenyl and trifluoroacetyl groups, making it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily needed by research and development laboratories, as well as production facilities in the pharmaceutical and agrochemical industries, for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing novel fluorinated polymers, liquid crystals, and other advanced materials with unique thermal and chemical resistance.
• Organic Synthesis & Process Chemistry: Employed as a versatile reagent in academic and industrial R&D for constructing complex heterocycles and introducing trifluoroacetyl functional groups.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects requiring high-purity, specialized fluorinated intermediates.

Basic Information

Product Name	n-(2,4-Difluorophenyl)-2,2,2-Trifluoroacetamide
CAS No.	98651-71-9
Molecular Formula	C8H4F5NO
Molecular Weight	225.12 g/mol
Synonyms	2,2,2-Trifluoro-N-(2,4-difluorophenyl)acetamide; 2',4'-Difluoro-2,2,2-trifluoroacetamilide; N-(2,4-Difluorophenyl)trifluoroacetamide; 98651-71-9; 2,4-DFTA; TFAA-2,4-DFA; Acetamide, N-(2,4-difluorophenyl)-2,2,2-trifluoro-
EINECS	Contact for details

Quality Control

Our n-(2,4-Difluorophenyl)-2,2,2-Trifluoroacetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications for research and production use. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.