Description

γ-Msh (3-8) CAS NO 98640-70-1 is a synthetic peptide fragment corresponding to the active core sequence of γ-melanocyte-stimulating hormone. This compound is a critical research tool for studying melanocortin receptor signaling pathways and their physiological roles. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on metabolic regulation, inflammation, and skin pigmentation studies.

Application

• Biomedical Research: Used as a reference standard and agonist in studies targeting melanocortin receptors (MC1R, MC3R, MC4R, MC5R).
• Pharmacology Development: Serves as a key intermediate or lead compound in the discovery of novel therapeutics for obesity, cachexia, and sexual dysfunction.
• Cell Signaling Studies: Employed to investigate intracellular pathways related to anti-inflammatory responses and immunomodulation.
• Dermatology Research: Applied in vitro and in vivo models to understand mechanisms of skin pigmentation and photoprotection.
• Neuroscience: Used to explore the role of melanocortins in feeding behavior, energy homeostasis, and neuroprotection.
• Analytical Standard: Functions as a high-purity calibrant in HPLC, LC-MS, and other analytical methods for peptide quantification and identification.

Basic Information

Item	Details
Product Name	γ-Msh (3-8)
CAS No.	98640-70-1
Molecular Formula	C₃₄H₅₀N₁₂O₈
Molecular Weight	746.84 g/mol
Synonyms	γ-MSH (3-8); γ-MSH (3-8); Melanotropin gamma (3-8); H-Tyr-Val-Met-Gly-His-Phe-OH; L-Tyrosyl-L-valyl-L-methionylglycyl-L-histidyl-L-phenylalanine; Tyr-Val-Met-Gly-His-Phe; γ-MSH3-8; Melanocortin peptide fragment
EINECS	Contact for details

Quality Control

Our γ-Msh (3-8) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing exact purity, impurity profile, and analytical results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature in a dry atmosphere before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80.0% (by AAA)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.