Description

2-(2-Fluoro-Benzyl)-3-Oxo-Butyric Acid Methyl Ester is a high-purity fluorinated organic intermediate with significant synthetic utility. This compound is valued for its role as a versatile building block in advanced pharmaceutical and agrochemical research and development. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated benzyl or β-keto ester motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Employed as a scaffold or labeling reagent in the design of enzyme inhibitors, probes, and other bioactive tools.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.
• Custom Synthesis & Scale-Up: A critical starting material for custom manufacturing and process optimization projects requiring reliable, high-quality fluorinated intermediates.

Basic Information

Product Name	2-(2-Fluoro-Benzyl)-3-Oxo-Butyric Acid Methyl Ester
CAS No.	98601-37-7
Molecular Formula	C12H13FO3
Molecular Weight	224.23 g/mol
Synonyms	Methyl 2-(2-Fluorobenzyl)-3-oxobutanoate; 3-Oxo-2-[(2-fluorophenyl)methyl]butanoic Acid Methyl Ester; 2-(2-Fluorobenzyl)acetoacetic Acid Methyl Ester; Methyl 2-(2-Fluorobenzyl)acetoacetate; 2-(2-Fluorobenzyl)-3-oxobutyric Acid Methyl Ester; Acetoacetic Acid 2-(2-Fluorobenzyl) Methyl Ester
EINECS	Contact for details

Quality Control

Our 2-(2-Fluoro-Benzyl)-3-Oxo-Butyric Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.