Description

2,3-Bis-(Palmitoyloxy)-2-Propyl-n-Palmitoyl-Cysteinylserine is a synthetic, multi-palmitoylated lipopeptide derivative. This compound is of significant interest for its role as a key structural component in the development of advanced lipid-based delivery systems and immunomodulatory agents. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors. The material is designed for applications requiring precise molecular architecture to mimic natural lipid environments or to act as a functional adjuvant.

Application

• Lipid Nanoparticle (LNP) Formulation: A critical building block for constructing stable, biocompatible lipid nanoparticles used in mRNA and siRNA delivery.
• Vaccine Adjuvant Development: Serves as a synthetic analog in the research and production of novel vaccine adjuvants to enhance immune response.
• Model Membrane Systems: Used in biophysical studies to create synthetic lipid bilayers and vesicles that mimic cell membranes.
• Drug Delivery Carriers: Incorporated into liposomal and other nanocarrier systems to improve drug encapsulation efficiency and targeted release.
• Bioconjugation & Probe Synthesis: Acts as a functionalized lipid anchor for conjugating peptides, proteins, or fluorescent probes in diagnostic tool development.
• Cosmetic Actives Stabilization: Employed in high-end cosmetic formulations to stabilize and deliver sensitive active ingredients.

Basic Information

Item	Detail
Product Name	2,3-Bis-(Palmitoyloxy)-2-Propyl-n-Palmitoyl-Cysteinylserine
CAS No.	98598-79-9
Molecular Formula	C57H107NO9S
Molecular Weight	974.53 g/mol
Synonyms	Pam3Cys-Ser; N-Palmitoyl-S-[2,3-bis(palmitoyloxy)propyl]-L-cysteinyl-L-serine; S-[2,3-Bis(palmitoyloxy)propyl] [N-palmitoyl]cysteinylserine; Tripalmitoyl-S-glyceryl cysteinylserine; TLR1/TLR2 Agonist Pam3CSK4 analog; Synthetic Lipopeptide; Lipoprotein Mimetic; TLR-2 Ligand
EINECS	Contact for details

Quality Control

Our 2,3-Bis-(Palmitoyloxy)-2-Propyl-n-Palmitoyl-Cysteinylserine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.