Description

Neuromedin U 25 is a synthetic peptide analog of the endogenous neuropeptide neuromedin U, a potent regulator of energy homeostasis and smooth muscle contraction. This high-purity compound is critical for advanced research in neuroendocrinology and metabolic disorders, providing a reliable tool for receptor binding studies and functional assays. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel therapeutics for obesity, diabetes, and gastrointestinal motility disorders.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies targeting NMU receptor subtypes (NMU1R and NMU2R) to elucidate signaling pathways.
• Drug Discovery & Development: Serves as a key intermediate or lead compound in screening programs for metabolic and cardiovascular diseases.
• Biochemical Assays: Employed in competitive binding assays (e.g., radioimmunoassays, ELISA) and functional cellular assays to measure receptor activity and potency.
• Academic & Clinical Research: Supports fundamental research into the role of neuromedin U in appetite regulation, stress response, and inflammatory processes.
• Peptide Chemistry: Acts as a substrate for structure-activity relationship (SAR) studies to develop more stable or selective peptide analogs.

Basic Information

Product Name	Neuromedin U 25
CAS No.	98530-28-0
Molecular Formula	C₁₄₀H₂₂₀N₄₄O₄₂S₂
Molecular Weight	3169.6 g/mol
Synonyms	Neuromedin U-25; NMU-25; hNMU-25; Human Neuromedin U (1-25); Neuromedin U (human); Tyr-Lys-Val-Asn-Glu-Tyr-Glu-Leu-Pro-Arg-Pro-Arg-Asn-Arg-Tyr-Gly-Leu-Phe-Thr-Pro-Arg-Asn-Arg-Phe-NH₂; H-Tyr-Lys-Val-Asn-Glu-Tyr-Glu-Leu-Pro-Arg-Pro-Arg-Asn-Arg-Tyr-Gly-Leu-Phe-Thr-Pro-Arg-Asn-Arg-Phe-NH₂
EINECS	Contact for details

Quality Control

Every batch of Neuromedin U 25 is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, MS, and amino acid analysis. Our quality standards are designed to meet the rigorous demands of pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and storage under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.