Description

Proline, 5-Carbamoyl- (6Ci) is a specialized proline derivative characterized by a carbamoyl functional group at the 5-position. This compound serves as a valuable non-proteinogenic amino acid building block and a key synthetic intermediate in advanced organic synthesis. It is primarily utilized by research institutions and industrial R&D departments focused on pharmaceutical development, peptide chemistry, and agrochemical research.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or designed as peptide mimetics.
• Peptide Synthesis Building Block: Used to incorporate modified proline residues into custom peptides for structure-activity relationship (SAR) studies and bioactive peptide development.
• Agrochemical Research: Serves as a synthetic intermediate in the development of new herbicides, fungicides, or plant growth regulators with novel modes of action.
• Biochemical Research: Employed in enzymatic studies and as a substrate or inhibitor analog for research on proline-metabolizing enzymes.
• Chemical Biology Probe Development: Used to create labeled or tagged molecular probes for investigating biological pathways and protein interactions.
• Fine Chemical Synthesis: Acts as a chiral synthon for the asymmetric synthesis of complex natural products and other high-value specialty chemicals.

Basic Information

Item	Detail
Product Name	Proline, 5-Carbamoyl- (6Ci)
CAS No.	98484-65-2
Molecular Formula	C6H10N2O3
Molecular Weight	158.16 g/mol
Synonyms	5-Carbamoylproline; 5-Carbamoyl-L-proline; 5-Carbamoyl-DL-proline; 5-Ureidopentanoic acid, cyclic; 2-Pyrrolidinecarboxylic acid, 5-carbamoyl-; 5-Carbamoylpyrrolidine-2-carboxylic acid; 5-Aminocarbonylproline; 5-Carbamoyl-2-pyrrolidinecarboxylic acid
EINECS	Contact for details

Quality Control

Our Proline, 5-Carbamoyl- (6Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. For custom purity grades or specific impurity profiles, please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Optical Rotation (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.