Description

6,8-Dibromo-4-Chloro-Quinazoline is a halogenated quinazoline derivative, a versatile and high-value synthetic intermediate in advanced organic chemistry. Its precise molecular architecture makes it a critical building block for constructing complex heterocyclic compounds, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on targeted therapies, agrochemicals, and advanced material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors and other biologically active quinazoline-based drug candidates.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the quinazoline core into more complex molecular systems.
• Academic & R&D: A valuable reagent for studying structure-activity relationships (SAR) and developing new synthetic methodologies in heterocyclic chemistry.

Basic Information

Product Name	6,8-Dibromo-4-Chloro-Quinazoline
CAS No.	98436-45-4
Molecular Formula	C8H3Br2ClN2
Molecular Weight	346.38 g/mol
Synonyms	4-Chloro-6,8-dibromoquinazoline; 6,8-Dibromo-4-chloroquinazoline; Quinazoline, 6,8-dibromo-4-chloro-; 98436-45-4; 4-Chloro-6,8-dibromo-quinazoline
EINECS	Contact for details

Quality Control

Our 6,8-Dibromo-4-Chloro-Quinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.