Description

1-Ethyl-L-Proline is a chiral, non-proteinogenic amino acid derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and high-purity building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as peptide mimetics and chiral catalyst synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic disorders.
• Peptidomimetics & Constrained Peptides: Used to introduce conformational rigidity and modify the pharmacokinetic properties of peptide-based drug candidates.
• Asymmetric Catalysis: Serves as a precursor or ligand in the development of chiral catalysts for enantioselective synthesis.
• Agrochemical Research: Employed in the design and synthesis of novel, bioactive compounds with specific stereochemical requirements.
• Biochemical Tool Development: Utilized in the creation of probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	1-Ethyl-L-Proline
CAS No.	98435-76-8
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	L-Proline, 1-ethyl-; (S)-1-Ethylpyrrolidine-2-carboxylic acid; 1-Ethyl-L-proline; 1-Ethylproline; (2S)-1-Ethylpyrrolidine-2-carboxylic acid; 98435-76-8; 1-Ethyl-(S)-proline
EINECS	Contact for details

Quality Control

Our 1-Ethyl-L-Proline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.