Description

8-Bromo-7-(3-Chloropropyl)-1,3-Dimethyl-2,3,6,7-Tetrahydro-1H-Purine-2,6-Dione is a high-purity, advanced pharmaceutical intermediate of significant interest in modern organic synthesis. This compound matters for its role as a key building block in the development of novel therapeutic agents, particularly within the xanthine and purine derivative families. Pharmaceutical R&D and fine chemical synthesis laboratories require this material for its specific bromo- and chloropropyl functional groups, which enable targeted molecular modifications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential adenosine receptor antagonists and other purine-based bioactive molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates targeting neurological and cardiovascular pathways.
• Fine Chemical Synthesis: Serves as a versatile scaffold for introducing specific halogenated alkyl chains into complex heterocyclic systems.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition and receptor-ligand interactions related to purinergic signaling.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) engaged in cutting-edge organic and medicinal chemistry projects.

Basic Information

Product Name	8-Bromo-7-(3-Chloropropyl)-1,3-Dimethyl-2,3,6,7-Tetrahydro-1H-Purine-2,6-Dione
CAS No.	98408-17-4
Molecular Formula	C₁₀H₁₂BrClN₄O₂
Molecular Weight	335.58 g/mol
Synonyms	8-Bromo-7-(3-chloropropyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione; 8-Bromo-7-(3-chloropropyl)theophylline; 1,3-Dimethyl-8-bromo-7-(3-chloropropyl)xanthine; 98408-17-4; 8-Bromo-7-(3-chloropropyl)-1,3-dimethylxanthine; NSC 339586; Theophylline, 8-bromo-7-(3-chloropropyl)-; Purine-2,6-dione, 8-bromo-7-(3-chloropropyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-
EINECS	Contact for details

Quality Control

Our 8-Bromo-7-(3-Chloropropyl)-1,3-Dimethyl-2,3,6,7-Tetrahydro-1H-Purine-2,6-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.