Description

Neuromedin U-25 (Porcine) is a bioactive neuropeptide fragment derived from the porcine neuromedin U precursor. This compound is a critical research tool for studying the neuromedin U receptor system, which plays a significant role in regulating energy homeostasis, gastrointestinal motility, and stress responses. It is essential for researchers and developers in the fields of neuroendocrinology, metabolic disorder research, and pharmaceutical discovery.

Application

• Neuroscience Research: Used as a reference standard and agonist in receptor binding assays and functional studies to elucidate the role of the NMU system in the central and peripheral nervous systems.
• Metabolic Disorder Studies: Applied in preclinical research to investigate its effects on food intake, energy expenditure, and body weight regulation for potential anti-obesity therapeutics.
• Gastrointestinal Physiology: Employed to study the peptide's potent contractile effects on smooth muscle in the gut, relevant for understanding motility disorders.
• Cardiovascular Research: Utilized in models to examine its influence on blood pressure and heart rate regulation.
• Pharmaceutical Development: Serves as a key biological tool for high-throughput screening (HTS) and validation of novel NMU receptor-targeted drug candidates.
• Antibody Production & Immunoassays: Acts as an antigen for the generation of specific antibodies used in ELISA, RIA, and immunohistochemistry applications.

Basic Information

Product Name	Neuromedin U-25 (Porcine)
CAS No.	98395-76-7
Molecular Formula	C₁₂₉H₂₁₃N₄₁O₄₀
Molecular Weight	2952.3 g/mol
Synonyms	Neuromedin U-25, porcine; NMU-25 (porcine); Neuromedin U (25-50), porcine; H-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2 (Disulfide bridge: Cys8-Cys16); Porcine Neuromedin U-25; NMU-25; pNMU-25; Neuromedin U (pNMU-25)
EINECS	Contact for details

Quality Control

Our Neuromedin U-25 (Porcine) is produced under stringent conditions to ensure the highest standards of purity and biological activity. Each batch undergoes comprehensive analytical testing, including reverse-phase HPLC for purity assessment and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are provided to guarantee consistency and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical
Solvent Residues	Meets ICH guidelines
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.