Description

Ac-Glu(Osu)-Obzl CAS NO 98318-09-3 is a protected glutamic acid derivative, specifically an N-acetyl glutamic acid active ester with a benzyl protecting group. This compound is a crucial building block in peptide synthesis and organic chemistry, offering controlled reactivity for the selective formation of amide bonds. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptides, prodrugs, and other bioactive molecules.

Application

• Peptide Synthesis: Serves as a key protected glutamic acid residue for the solid-phase or solution-phase synthesis of complex peptides.
• Bioconjugation: Used as a linker or spacer molecule for attaching peptides or other functional groups to larger biomolecules, surfaces, or polymers.
• Pharmaceutical Intermediates: Acts as a critical intermediate in the research and development of potential therapeutic agents targeting neurological and metabolic pathways.
• Chemical Biology Probes: Employed in the design and synthesis of probes for studying enzyme activity, protein-protein interactions, and cellular processes.
• Material Science: Can be utilized in the development of functionalized polymers and smart materials with peptide-based components.

Basic Information

Product Name	Ac-Glu(Osu)-Obzl
CAS No.	98318-09-3
Molecular Formula	C16H18N2O7
Molecular Weight	350.33 g/mol
Synonyms	N-Acetyl-L-glutamic acid 5-benzyl ester N-hydroxysuccinimide ester; Nα-Acetyl-L-glutamic acid γ-benzyl ester N-succinimidyl ester; Ac-Glu(OBzl)-OSu; Ac-L-Glu(OBzl)-OSu; Benzyl Nα-acetyl-L-glutamate N-succinimidyl ester; N-Succinimidyl N-acetyl-L-glutamate 5-benzyl ester; Ac-Glu-OBzl-OSu; Glutamic acid derivative 98318-09-3
EINECS	Contact for details

Quality Control

Our Ac-Glu(Osu)-Obzl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.