Description

2-Amino-6-(4-Fluorophenyl)Pyrimidin-4(3H)-One is a high-purity fluorinated pyrimidinone derivative, a critical building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with tailored biological and material properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Biology: Employed as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring fluorinated heterocycles.

Basic Information

Product Name	2-Amino-6-(4-Fluorophenyl)Pyrimidin-4(3H)-One
CAS No.	98305-74-9
Molecular Formula	C10H8FN3O
Molecular Weight	205.19 g/mol
Synonyms	6-(4-Fluorophenyl)-2-amino-4(3H)-pyrimidinone; 2-Amino-6-(4-fluorophenyl)-4(3H)-pyrimidinone; 2-Amino-6-(p-fluorophenyl)-4-pyrimidinol; 4(3H)-Pyrimidinone, 2-amino-6-(4-fluorophenyl)-; 2-Amino-6-(4-fluorophenyl)pyrimidin-4-ol; 6-(4-Fluorophenyl)-2-aminopyrimidin-4(3H)-one
EINECS	Contact for details

Quality Control

Our 2-Amino-6-(4-Fluorophenyl)Pyrimidin-4(3H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.