Description

3-Hydroxy-3-(Trifluoromethyl)Indolin-2-One is a high-value, fluorinated indolinone derivative that serves as a critical synthetic intermediate. Its molecular structure, featuring both a hydroxyl group and a trifluoromethyl moiety, makes it a versatile building block for constructing complex molecules with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves efficacy and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and advanced organic materials with unique electronic or surface properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A pivotal starting material for custom synthesis projects requiring fluorinated heterocyclic scaffolds.

Basic Information

Product Name	3-Hydroxy-3-(Trifluoromethyl)Indolin-2-One
CAS No.	98294-08-7
Molecular Formula	C9H6F3NO2
Molecular Weight	217.15 g/mol
Synonyms	3-Hydroxy-3-(trifluoromethyl)-2-indolinone; 3-Hydroxy-3-(trifluoromethyl)indolin-2-one; 2H-Indol-2-one, 3-hydroxy-3-(trifluoromethyl)-1,3-dihydro-; 3-(Trifluoromethyl)-3-hydroxyindolin-2-one; 3-Hydroxy-3-trifluoromethyloxindole; 3-Trifluoromethyl-3-hydroxyoxindole; 3-Hydroxy-3-trifluoromethyl-2-oxindole
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-3-(Trifluoromethyl)Indolin-2-One is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.