Description

Isovaline, 3-Mercapto- (9Ci) is a specialized non-proteinogenic amino acid derivative featuring a unique thiol-functionalized side chain. This compound is valued for its role as a versatile chiral building block and a precursor in the synthesis of complex bioactive molecules. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for applications in medicinal chemistry and asymmetric synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) targets.
• Peptide Mimetics & Modifications: Used to introduce thiol functionality into peptide chains, enabling disulfide bridge formation or conjugation for drug delivery systems.
• Asymmetric Catalyst Ligand Precursor: Acts as a starting material for synthesizing chiral ligands used in metal-catalyzed asymmetric reactions.
• Agrochemical Research: Employed in the development of new herbicides or plant growth regulators with specific stereochemical requirements.
• Biochemical Research: Utilized in studies of enzyme mechanisms, metabolic pathways, and as a substrate analog in biochemical assays.
• Fine Chemical Synthesis: A building block for creating complex, high-value specialty chemicals with defined stereochemistry.

Basic Information

Product Name	Isovaline, 3-Mercapto- (9Ci)
CAS No.	98119-54-1
Molecular Formula	C5H11NO2S
Molecular Weight	149.21 g/mol
Synonyms	3-Mercaptoisovaline; (R,S)-3-Mercapto-2-methylbutanoic acid; 2-Methyl-3-sulfanylbutyric acid; 3-Thiol-isovaline; DL-3-Mercaptoisovaline; 3-Mercapto-2-methylbutyric acid; (±)-3-Mercaptoisovaline; 2-Methyl-3-mercaptobutyric acid
EINECS	Contact for details

Quality Control

Our Isovaline, 3-Mercapto- (9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its hygroscopic and easily oxidized nature, containers must be kept tightly sealed and opened under an inert environment to minimize moisture uptake and oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.