Description

3-Quinolinecarboxylic Acid, 6-Fluoro-1,4-Dihydro-4-Oxo-1-Phenyl-7-(1-Piperazinyl)- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs).

Application

• Key Intermediate in Fluoroquinolone Antibiotic Synthesis: Serves as a crucial building block for the development of next-generation antibacterial agents.
• Pharmaceutical Research & Development: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the scaled-up production of specific antibiotic and antimicrobial drugs.
• Biochemical Research: Utilized as a tool compound in studies targeting bacterial DNA gyrase and topoisomerase IV enzymes.
• Contract Manufacturing Organizations (CMOs): Supplied to CMOs specializing in the custom synthesis of complex molecules for clinical trials.
• Academic Research: Used in university and institutional labs for advanced organic synthesis and pharmacological studies.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 6-Fluoro-1,4-Dihydro-4-Oxo-1-Phenyl-7-(1-Piperazinyl)-
CAS No.	98106-13-9
Molecular Formula	C20H17FN4O3
Molecular Weight	380.37 g/mol
Synonyms	6-Fluoro-1,4-dihydro-4-oxo-1-phenyl-7-(1-piperazinyl)-3-quinolinecarboxylic acid; 7-(1-Piperazinyl)-6-fluoro-1-phenyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid; PD 117596; ABT-719 precursor; Fluoroquinolone intermediate; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid derivative; 7-Piperazinyl-6-fluoroquinolone-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid, 6-Fluoro-1,4-Dihydro-4-Oxo-1-Phenyl-7-(1-Piperazinyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) documenting full specifications are available upon request, and we can support custom purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.