Description

4-Pyrimidinethiol, 6-Chloro- (6Ci) is a high-purity heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides due to its reactive thiol and chloro substituents.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized heterocyclic compounds for organic electronic materials and polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Pyrimidinethiol, 6-Chloro- (6Ci)
CAS No.	98027-08-8
Molecular Formula	C4H3ClN2S
Molecular Weight	146.60 g/mol
Synonyms	6-Chloro-4-pyrimidinethiol; 6-Chloro-4-mercaptopyrimidine; 4-Mercapto-6-chloropyrimidine; 6-Chloro-1H-pyrimidine-4-thione; 6-Chloro-4-pyrimidinol, thio-; 6-Chloro-4(1H)-pyrimidinethione; 6-Chloro-4-thioxo-3,4-dihydropyrimidine; 6-Chloro-4-thiopyrimidone
EINECS	Contact for details

Quality Control

Our 4-Pyrimidinethiol, 6-Chloro- (6Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.