Description

2-Chloro-Pyrimidine-5-Sulfonyl Chloride is a high-purity, reactive bifunctional intermediate essential for advanced organic synthesis. This compound matters because it serves as a critical building block for introducing both chloropyrimidine and sulfonyl chloride functionalities in a single step, enabling efficient derivatization. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, antiviral agents, and other small molecule APIs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and plant growth regulators with pyrimidine cores.
• Material Science Research: Serves as a monomer or cross-linking agent for developing functional polymers and advanced materials.
• Chemical Biology Probes: Utilized in designing activity-based probes and affinity labels for target identification and validation studies.
• Custom Synthesis & Contract Manufacturing: A vital reagent for CDMOs and fine chemical suppliers producing tailored compounds for client projects.

Basic Information

Product Name	2-Chloro-Pyrimidine-5-Sulfonyl Chloride
CAS No.	98026-88-1
Molecular Formula	C4H2Cl2N2O2S
Molecular Weight	228.04 g/mol
Synonyms	2-Chloropyrimidine-5-sulfonyl chloride; 5-(Chlorosulfonyl)-2-chloropyrimidine; Pyrimidine-5-sulfonyl chloride, 2-chloro-; 2-Chloro-5-pyrimidinesulfonyl chloride; 98026-88-1; 2-Chloropyrimidine-5-sulphonyl chloride; 2-Chloro-5-sulfonylchloride pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-Pyrimidine-5-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full traceability are provided to guarantee compliance with your project specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.