Description

6-Amino-4-Phenyl-2-Thioxo-1,2,3,4-Tetrahydro-Pyrimidine-5-Carboxylic Acid Amide is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmacologically active molecules, particularly within the pyrimidine and thiouracil derivative families. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, drug discovery, and the synthesis of complex organic intermediates.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or acting as nucleoside analogs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic agents.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex fused-ring heterocyclic systems in academic and industrial R&D.
• Biochemical Research: Potential use in the development of biochemical probes and enzyme substrates due to its specific molecular scaffold.
• Agrochemical Intermediate: Can be utilized in the research and development of new crop protection agents and pesticides.
• Material Science Precursor: Investigated for the synthesis of specialized organic compounds with potential applications in advanced materials.

Basic Information

Product Name	6-Amino-4-Phenyl-2-Thioxo-1,2,3,4-Tetrahydro-Pyrimidine-5-Carboxylic Acid Amide
CAS No.	98011-28-0
Molecular Formula	C11H12N4OS
Molecular Weight	248.30 g/mol
Synonyms	6-Amino-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide; 4-Phenyl-6-amino-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid amide; 5-Carbamoyl-6-amino-4-phenyl-3,4-dihydro-2(1H)-pyrimidinethione; 98011-28-0; 6-Amino-4-phenyl-2-mercapto-3,4-dihydropyrimidine-5-carboxamide; 4-Phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid amide, 6-amino-; 6-Amino-4-phenyl-1,2,3,4-tetrahydro-2-thioxopyrimidine-5-carboxamide
EINECS	Contact for details

Quality Control

Our 6-Amino-4-Phenyl-2-Thioxo-1,2,3,4-Tetrahydro-Pyrimidine-5-Carboxylic Acid Amide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.