Description

Parathyroid Hormone (1-34) Amide, Nle(8), Nle(18), Tyr(34)- CAS NO 97930-52-4 is a synthetic bioactive peptide fragment of human parathyroid hormone (PTH), engineered with specific amino acid substitutions to enhance its stability and biological activity. This analog is critical for research and development in bone metabolism and calcium homeostasis, offering a potent and reliable tool for studying PTH receptor signaling. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotech companies focused on developing novel therapeutics for osteoporosis and other metabolic bone disorders.

Application

• Pharmaceutical Research & Development: As a reference standard and active agent in preclinical studies for osteoporosis and hypoparathyroidism treatments.
• Biochemical Assay Development: Used in cell-based assays and receptor binding studies to investigate PTH1R (PTH/PTHrP receptor) activation and downstream signaling pathways.
• Academic Research: Fundamental studies in endocrinology, calcium and phosphate metabolism, and bone biology.
• Peptide Chemistry Studies: Serves as a model compound for studying structure-activity relationships (SAR) in peptide hormone analogs.
• Quality Control & Analytical Standards: Employed as a high-purity calibrant in HPLC, LC-MS, and other analytical methods within quality control laboratories.

Basic Information

Product Name	Parathyroid Hormone (1-34) Amide, Nle(8), Nle(18), Tyr(34)- CAS NO 97930-52-4
CAS No.	97930-52-4
Molecular Formula	C181H291N55O51S2
Molecular Weight	4107.7 g/mol
Synonyms	PTH (1-34) amide, [Nle8,18, Tyr34]-hPTH(1-34) amide; Teriparatide Acetate analog; hPTH(1-34) amide, Nle8,18, Tyr34; Parathyroid Hormone Fragment 1-34 amide (human); PTH 1-34 (amide); [Nle8,18,Tyr34]PTH(1-34)NH2; CAS 97930-52-4
EINECS	Contact for details

Quality Control

Our Parathyroid Hormone (1-34) Amide, Nle(8), Nle(18), Tyr(34)- CAS NO 97930-52-4 is manufactured under strict quality systems suitable for research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). A detailed Certificate of Analysis (COA) providing batch-specific results is supplied with every shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.