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Lhrh, His(5)-Arg(6)-Trp(7)-Tyr(8)- CAS NO 97850-15-2


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CAS No.:97850-15-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Lhrh, His(5)-Arg(6)-Trp(7)-Tyr(8)- CAS NO 97850-15-2 is a synthetic peptide fragment derived from the Luteinizing Hormone-Releasing Hormone (LHRH) sequence, specifically encompassing the 5-8 amino acid residues. This high-purity peptide intermediate is critical for advanced pharmaceutical research and development, particularly in the synthesis of hormone analogs and diagnostic agents. It serves as a vital building block for researchers and manufacturers in the fields of endocrinology, oncology, and reproductive medicine, where precise molecular structure and batch-to-batch consistency are paramount.

Application

  • Pharmaceutical Intermediate: Primary use as a key synthetic fragment in the production of LHRH analogs and related therapeutic peptides.
  • Research & Development: Essential tool for biochemical research, structure-activity relationship (SAR) studies, and hormone signaling pathway investigations.
  • Diagnostic Reagent Synthesis: Used in the development of labeled compounds and tracers for diagnostic assays and imaging.
  • Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in peptide analysis.
  • Bioconjugation: Utilized as a starting material for creating peptide-drug conjugates or other bioconjugates for targeted therapies.

Basic Information

Product Name Lhrh, His(5)-Arg(6)-Trp(7)-Tyr(8)- CAS NO 97850-15-2
CAS No. 97850-15-2
Molecular Formula C₃₃H₄₅N₁₃O₇
Molecular Weight 735.80 g/mol
Synonyms LHRH (5-8); Luteinizing Hormone-Releasing Hormone Fragment (5-8); His-Arg-Trp-Tyr; H-R-W-Y; Gonadorelin (5-8); Pyroglutamyl-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH₂ (5-8 fragment); LH-RH (5-8); pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH₂ (5-8)
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Quality Control

Our Lhrh, His(5)-Arg(6)-Trp(7)-Tyr(8)- is manufactured under strict quality systems to ensure the highest standards of purity and identity for research and pharmaceutical applications. Each batch is characterized by advanced analytical techniques including HPLC, MS, and NMR. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and can be tailored to meet specific pharmacopeial (e.g., USP) or client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (MS) Conforms to structure
Purity (HPLC) ≥ 98.0%
Single Impurity (HPLC) ≤ 1.0%
Water Content (KF) ≤ 5.0%
Peptide Content ≥ 80.0%
Acetate Content (HPLC) ≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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