Description

1,3-Propanediol, 2-[2-(2-Amino-6-Methoxy-9H-Purin-9-Yl)Ethyl]- is a high-purity, functionalized nucleoside derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in creating next-generation nucleotide analogs and prodrugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for novel antiviral and anticancer nucleotide analog drugs.
• Prodrug Development: Used in research to create masked or targeted forms of active nucleoside pharmaceuticals to improve bioavailability and reduce side effects.
• Bioconjugation: The functionalized propanediol moiety allows for conjugation with peptides, antibodies, or other targeting ligands in advanced drug delivery systems.
• Chemical Biology Research: Employed as a tool compound or labeled probe to study enzyme mechanisms, such as those of polymerases and kinases.
• Nucleic Acid Chemistry: Potential use in the synthesis of modified oligonucleotides for therapeutic (e.g., antisense, siRNA) or diagnostic applications.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory filings in pharmaceutical manufacturing.

Basic Information

Item	Details
Product Name	1,3-Propanediol, 2-[2-(2-Amino-6-Methoxy-9H-Purin-9-Yl)Ethyl]-
CAS No.	97845-65-3
Molecular Formula	C11H17N5O3
Molecular Weight	267.28 g/mol
Synonyms	2-[2-(2-Amino-6-methoxy-9H-purin-9-yl)ethyl]-1,3-propanediol; 9-[2-(2,3-Dihydroxypropyl)ethyl]-2-amino-6-methoxypurine; 2-Amino-6-methoxy-9-(2,3-dihydroxypropyl)ethylpurine; 6-Methoxy-2-aminopurine propanediol derivative; 9-(2,3-Dihydroxypropyl)-2-amino-6-methoxypurine; A Modified Nucleoside Base; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 1,3-Propanediol, 2-[2-(2-Amino-6-Methoxy-9H-Purin-9-Yl)Ethyl]- is manufactured under strict quality management systems suitable for research and development use. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While produced to high standards, this product is currently intended for R&D purposes and not for drug, food, or household use. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Single Maximum Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.