Description

Vasopressin, 1-Deamino-(3-(4-Azido-Phe))-8-Lys- is a synthetic, photoactivatable analog of the neurohypophyseal hormone vasopressin, specifically engineered for advanced biochemical research. This compound is a critical tool for investigating vasopressin receptor structure, function, and signaling pathways through covalent cross-linking techniques. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotech companies focused on endocrinology, neurobiology, and drug discovery. The product is supplied to meet the stringent purity requirements necessary for sensitive biological assays and molecular studies.

Application

• Photoaffinity Labeling Studies: Acts as a covalent probe for mapping vasopressin (V1a, V1b, V2) receptor binding sites and identifying interacting proteins.
• Structural Biology Research: Used in cross-linking experiments to stabilize peptide-receptor complexes for analysis via X-ray crystallography or cryo-electron microscopy.
• Signal Transduction Analysis: Enables the study of G-protein coupled receptor (GPCR) activation and downstream signaling cascades triggered by vasopressin receptors.
• Drug Discovery & Development: Serves as a key intermediate or reference standard in the design and screening of novel vasopressin receptor agonists and antagonists.
• Biochemical Assay Development: Employed as a high-affinity, irreversible ligand in the development of robust receptor binding and functional assays.
• Metabolic Pathway Investigation: Used to study the role of vasopressin in physiological processes such as water homeostasis, blood pressure regulation, and stress response.

Basic Information

Product Name	Vasopressin, 1-Deamino-(3-(4-Azido-Phe))-8-Lys-
CAS No.	97794-92-8
Molecular Formula	C52H74N16O12S2
Molecular Weight	1171.4 g/mol
Synonyms	1-Deamino-8-Lysine-vasopressin, 3-(4-Azido-Phe) analog; [1-Deamino, 3-(p-azido-Phe), 8-Lys]Vasopressin; p-Azido-Phe-Vasopressin analog; Photoactivatable vasopressin; AVP photoaffinity label; [Lys8]-Vasopressin, 1-deamino-3-(4-azido-Phe) derivative; Arginine vasopressin photoaffinity probe; V1/V2 receptor cross-linking agent
EINECS	Contact for details

Quality Control

Our Vasopressin, 1-Deamino-(3-(4-Azido-Phe))-8-Lys- is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, critical for reproducible research outcomes. Quality is verified through a comprehensive suite of analytical techniques including HPLC, MS, and NMR. A detailed Certificate of Analysis (COA) is provided with each batch, confirming identity, purity, and suitability for biochemical applications. Our quality system is designed to support GLP/GMP-compliant research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere. Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 2.0%
Solubility	Soluble in DMSO, Acetic Acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.