Description

Atriopeptin Iii CAS NO 97793-28-7 is a synthetic peptide fragment of the atrial natriuretic peptide (ANP) hormone, a key regulator of blood pressure and electrolyte balance. This high-purity compound is essential for advanced biochemical research and pharmaceutical development. It serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate for researchers and manufacturers in the cardiovascular and endocrine therapeutic fields.

Application

• Biochemical Research: Used as a reference standard and tool compound in studies of natriuretic peptide receptors (NPR-A, NPR-C) and their signaling pathways.
• Pharmaceutical R&D: Serves as a key intermediate or precursor in the synthesis of novel cardiovascular drugs targeting hypertension and heart failure.
• Diagnostic Development: Employed in the development and calibration of immunoassays (e.g., ELISA) for detecting ANP and related peptides.
• Mechanism of Action Studies: Critical for investigating the structure-activity relationships (SAR) of atrial natriuretic peptides.
• Academic Research: Utilized in university and institutional labs for cardiovascular physiology and pharmacology experiments.
• Peptide Library Screening: A component in high-throughput screening libraries for drug discovery programs.

Basic Information

Product Name	Atriopeptin Iii
CAS No.	97793-28-7
Molecular Formula	C106H166N34O30S2
Molecular Weight	~2392.8 g/mol
Synonyms	Atriopeptin 3; ANP (7-23); Atrial Natriuretic Peptide (7-23); H-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH (Disulfide bridge: Cys7-Cys23); Cardionatrin I (7-23); Auriculin A (7-23)
EINECS	Contact for details

Quality Control

Our Atriopeptin Iii is manufactured under strict quality systems to ensure batch-to-batch consistency for research and development. Each lot undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all specification parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.