Description

2-Amino-5-Iodobenzotrifluoride is a versatile halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino group and electron-withdrawing trifluoromethyl and iodo substituents, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the bioactivity of the trifluoromethyl group.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl structures.
• Dye and Pigment Manufacturing: Intermediate for producing specialized azo dyes and pigments with enhanced lightfastness and chemical stability.
• Chemical Biology Probes: Used to synthesize molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	2-Amino-5-Iodobenzotrifluoride
CAS No.	97760-97-9
Molecular Formula	C7H5F3IN
Molecular Weight	287.02 g/mol
Synonyms	5-Iodo-2-(trifluoromethyl)aniline; 2-Amino-α,α,α-trifluoro-5-iodotoluene; 2-Trifluoromethyl-5-iodoaniline; 5-Iodo-2-aminobenzotrifluoride; 2-Amino-5-iodo-α,α,α-trifluorotoluene; Benzenamine, 5-iodo-2-(trifluoromethyl)-; 5-Iodo-α,α,α-trifluoro-o-toluidine
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Iodobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.