Description

1H-Tetrazole-5-Carboxylic Acid, Methyl Ester (9Ci) is a versatile heterocyclic building block and a key synthon in modern organic synthesis. This compound is valued for its role as a precursor in the preparation of tetrazole-containing pharmaceuticals, agrochemicals, and energetic materials. It is primarily sought by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) containing the tetrazole moiety, a common bioisostere for carboxylic acids, used in drugs for hypertension (sartans) and other therapeutic areas.
• Agrochemical Synthesis: Employed in the development of novel herbicides, fungicides, and insecticides where the tetrazole ring contributes to biological activity and metabolic stability.
• Energetic Materials Research: Serves as a building block for high-nitrogen-content compounds and ligands in coordination chemistry for propellants and pyrotechnics.
• Coordination Chemistry & Ligand Synthesis: Used to create tetrazole-based ligands for metal-organic frameworks (MOFs) and catalysts.
• Peptide Chemistry & Bioconjugation: Acts as a coupling agent or a protected form of tetrazole-5-carboxylic acid for peptide synthesis and bioconjugation strategies.
• Material Science: A monomer or cross-linking agent in the development of specialty polymers with unique thermal or optical properties.

Basic Information

Product Name	1H-Tetrazole-5-Carboxylic Acid, Methyl Ester (9Ci)
CAS No.	97752-08-4
Molecular Formula	C3H4N4O2
Molecular Weight	128.09 g/mol
Synonyms	Methyl 1H-tetrazole-5-carboxylate; Methyl tetrazole-5-carboxylate; 5-Methoxycarbonyl-1H-tetrazole; 1H-Tetrazole-5-carboxylic acid methyl ester; Tetrazole-5-carboxylic acid methyl ester; 5-Carbomethoxy-1H-tetrazole; Methyl 5-tetrazolecarboxylate
EINECS	Contact for details

Quality Control

Our 1H-Tetrazole-5-Carboxylic Acid, Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.