Description

Somatotropin Releasing Hormone (1-32)Amide, His(1)-I-Tyr(10)-Nle(27)- is a synthetic peptide analog of growth hormone-releasing hormone (GHRH). This compound is engineered for enhanced stability and biological activity, making it a critical research tool for studying growth hormone regulation and secretion pathways. It is primarily utilized by pharmaceutical researchers, biotechnology companies, and academic institutions engaged in endocrinology, metabolic disorder research, and peptide-based therapeutic development.

Application

• Endocrine Research: Fundamental studies on the hypothalamic-pituitary axis and the mechanisms of growth hormone (GH) release.
• Drug Discovery & Development: Serving as a reference standard or active pharmaceutical ingredient (API) in preclinical research for novel GHRH-based therapies.
• Biochemical Assays: Used in in vitro and cell-based assays to evaluate receptor binding affinity and signal transduction.
• Metabolic Studies: Investigating the role of GHRH in growth, metabolism, and age-related disorders.
• Veterinary Science: Research into growth promotion and metabolic effects in agricultural animals.
• Quality Control: Acting as a high-purity standard for the analysis and validation of related peptide products.

Basic Information

Product Name	Somatotropin Releasing Hormone (1-32)Amide, His(1)-I-Tyr(10)-Nle(27)-
CAS No.	97741-14-5
Molecular Formula	C149H246N44O42S
Molecular Weight	~3359.9 g/mol
Synonyms	GHRH (1-32) amide, [His1,I-Tyr10,Nle27]-hGHRH(1-32)-NH2; Somatoliberin (1-32)amide derivative; Growth Hormone-Releasing Factor analog; GRF (1-32) amide analog; hpGRF(1-32)-NH2 analog; [Tyr10, Nle27]hGHRH(1-32)NH2; Modified hGHRH(1-32) peptide
EINECS	Contact for details

Quality Control

Our Somatotropin Releasing Hormone (1-32)Amide, His(1)-I-Tyr(10)-Nle(27)- is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability, purity, and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.