Description

Collagen I, Alpha Chain (98-110) is a specific, high-purity synthetic peptide fragment derived from the alpha chain of Type I Collagen, a primary structural protein in connective tissues. This defined sequence is crucial for research and development in biomaterials, tissue engineering, and targeted therapeutic studies. It is an essential biochemical tool for scientists and manufacturers in the pharmaceutical, cosmetic, and advanced biomedical sectors requiring precise molecular components.

Application

• Biomedical Research: Used as a standard or active component in studies of collagen structure, cell adhesion, and extracellular matrix interactions.
• Tissue Engineering Scaffolds: Incorporated into biomaterials to promote cell attachment, proliferation, and differentiation for regenerative medicine applications.
• Cosmetic & Dermatological Actives: Serves as a model peptide in the development of anti-aging and skin-repair formulations targeting collagen synthesis and skin barrier function.
• Immunological Studies: Employed in epitope mapping and the development of diagnostic assays or vaccines related to autoimmune disorders involving collagen.
• Pharmaceutical Development: Acts as a key intermediate or reference standard in the synthesis and quality control of peptide-based therapeutics.
• Biomaterial Coating: Used to functionalize surfaces of medical devices to enhance biocompatibility and integration with host tissue.

Basic Information

Product Name	Collagen I, Alpha Chain (98-110)
CAS No.	97653-85-5
Molecular Formula	C58H94N18O21
Molecular Weight	1355.5 g/mol
Synonyms	Collagen Type I Alpha 1 Chain (98-110); Collagen α-1(I) Chain Fragment 98-110; Gly-Pro-Hyp-Gly-Pro-Hyp-Gly-Ala-Hyp-Gly-Pro-Lys-Gly-Asp-Arg; GPOGPOGPAHGPRGDR; (Gly1, Pro2, Hyp3, Gly4, Pro5, Hyp6, Gly7, Ala8, Hyp9, Gly10, Pro11, Lys12, Gly13, Asp14, Arg15)-Peptide; Synthetic Collagen Peptide Fragment
EINECS	Contact for details

Quality Control

Our Collagen I, Alpha Chain (98-110) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for peptide synthesis, ensuring product integrity for critical applications in pharmaceuticals and biomedicine.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Amino Acid Composition	Conforms to theoretical values
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.