Description

2-(1'-Imidazoylsulfonyl)-1,3,5-Tri-o-Benzoyl-α-D-Ribofuranose is a sophisticated, high-purity nucleoside derivative used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise control over molecular structure and stereochemistry. It is primarily utilized in the development of novel pharmaceutical intermediates, particularly in antiviral and anticancer research, as well as in oligonucleotide synthesis for therapeutic and diagnostic applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of modified nucleosides and nucleotides for antiviral and anticancer drug candidates.
• Oligonucleotide Synthesis: Serves as a protected ribofuranose derivative for constructing complex RNA analogs and antisense oligonucleotides.
• Bioconjugation & Probe Development: Used in creating labeled nucleosides for diagnostic assays and molecular biology research tools.
• Glycosylation Chemistry: Acts as a glycosyl donor in stereoselective glycosylation reactions to build complex carbohydrate structures.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new bioactive molecules.
• Process Development & Scale-up: Supports the transition from laboratory-scale discovery to commercial manufacturing of active pharmaceutical ingredients (APIs).

Basic Information

Item	Details
Product Name	2-(1'-Imidazoylsulfonyl)-1,3,5-Tri-o-Benzoyl-α-D-Ribofuranose
CAS No.	97614-42-1
Molecular Formula	C31H25N3O9S
Molecular Weight	615.61 g/mol
Synonyms	1,3,5-Tri-O-benzoyl-2-[(imidazol-1-yl)sulfonyl]-α-D-ribofuranose; 2-(Imidazole-1-sulfonyl)-1,3,5-tri-O-benzoyl-α-D-ribofuranose; α-D-Ribofuranose, 2-(1H-imidazol-1-ylsulfonyl)-1,3,5-tris-O-(phenylcarbonyl)-; 2-Imidazolesulfonyl-1,3,5-tri-O-benzoyl-α-D-ribofuranose; 2-(Imidazol-1-ylsulfonyl)-1,3,5-tri-O-benzoyl-α-D-ribofuranose
EINECS	Contact for details

Quality Control

Our 2-(1'-Imidazoylsulfonyl)-1,3,5-Tri-o-Benzoyl-α-D-Ribofuranose is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and specific optical rotation measurement to ensure identity, strength, quality, and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.