Description

n-Acetyl-Transforming Growth Factor-Alph A Fragment is a chemically modified peptide fragment derived from Transforming Growth Factor-Alpha (TGF-α). This acetylated derivative is crucial for advanced biochemical research, offering enhanced stability and specific reactivity for studying receptor-ligand interactions and signal transduction pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on oncology, wound healing, and cell proliferation studies.

Application

• Biochemical Research: Used as a key reagent in studying the structure-activity relationship (SAR) of TGF-α and its interaction with the Epidermal Growth Factor Receptor (EGFR).
• Pharmaceutical Development: Serves as a reference standard or intermediate in the development of targeted cancer therapies and wound healing agents.
• Cell Culture Studies: Employed to investigate the effects of modified TGF-α fragments on cell proliferation, differentiation, and apoptosis in vitro.
• Proteomics & Signal Transduction: A tool for elucidating downstream signaling cascades activated by EGFR and related tyrosine kinase receptors.
• Antibody Production & Assay Development: Can be used as an antigen for generating specific antibodies or as a calibrator in immunoassays (e.g., ELISA).
• Academic Research: Fundamental research in molecular biology, oncology, and developmental biology to understand growth factor biology.

Basic Information

Product Name	n-Acetyl-Transforming Growth Factor-Alph A Fragment
CAS No.	97505-76-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ac-TGF-α Fragment; N-Acetyl TGF-alpha Fragment; Acetylated Transforming Growth Factor Alpha Peptide; TGF-α (Acetylated Fragment); CAS 97505-76-5; Ac-TGFα; Nα-Acetyl-Transforming Growth Factor-α Fragment
EINECS	Contact for details

Quality Control

Our n-Acetyl-Transforming Growth Factor-Alph A Fragment is produced under stringent conditions to ensure the highest standards of purity and consistency. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and MS for identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.