Description

(+)-5-Bromo-L-Histidine is a chiral, halogenated derivative of the essential amino acid L-Histidine. This compound is a valuable synthetic intermediate and building block in advanced organic and medicinal chemistry, prized for its role in modulating biological activity. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for the development of novel active compounds and biochemical probes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or receptor modulation.
• Biochemical Research: Used as a precursor or substrate in enzymatic studies and for the preparation of modified peptides and proteins.
• Agrochemical Development: Serves as an intermediate in the research and synthesis of new crop protection agents and plant growth regulators.
• Proteomics & Chemical Biology: Employed to create site-specifically labeled histidine residues for studying protein structure, function, and interactions.
• Diagnostic Reagent Synthesis: Potential use in the development of specialized reagents and contrast agents for diagnostic applications.

Basic Information

Product Name	(+)-5-Bromo-L-Histidine
CAS No.	97486-06-1
Molecular Formula	C6H9BrN3O2
Molecular Weight	235.06 g/mol
Synonyms	5-Bromo-L-histidine; (S)-2-Amino-3-(5-bromo-1H-imidazol-4-yl)propanoic acid; L-5-Bromohistidine; 5-Bromohistidine; 5-Br-His; H-5-Br-His-OH; Bromohistidine
EINECS	Contact for details

Quality Control

Our (+)-5-Bromo-L-Histidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing specific results for identity, purity, and impurities are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.