Description

n-Acetyl-Transforming Growth Factor-A Fragment 34-43 Methyl Ester Human is a synthetic peptide fragment derived from the human Transforming Growth Factor-A (TGF-A) sequence, specifically acetylated at the N-terminus and esterified at the C-terminus. This modification enhances its stability and makes it a crucial research-grade biochemical tool for studying TGF-A signaling pathways and receptor interactions. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on oncology, wound healing, and cell proliferation studies.

Application

• Biochemical Research: Used as a reference standard and active agent in studies investigating the structure-activity relationship (SAR) of Transforming Growth Factor-A.
• Cell Signaling Studies: Essential for in vitro assays to elucidate the mechanisms of TGF-A mediated cell proliferation, differentiation, and apoptosis.
• Pharmaceutical Development: Serves as a key intermediate or pharmacological tool in the discovery and development of therapeutics targeting growth factor pathways.
• Receptor Binding Assays: Employed in competitive binding experiments to characterize and quantify affinity for TGF-A receptors (e.g., EGFR).
• Academic Research: A vital reagent for university laboratories conducting fundamental research in molecular biology, oncology, and developmental biology.

Basic Information

Product Name	n-Acetyl-Transforming Growth Factor-A Fragment 34-43 Methyl Ester Human
CAS No.	97474-87-8
Molecular Formula	C58H85N15O16
Molecular Weight	1240.4 g/mol
Synonyms	Ac-TGF-A (34-43)-OMe; N-Acetyl-TGF-alpha (34-43) methyl ester; Ac-TGFα (34-43) methyl ester; Transforming Growth Factor Alpha Fragment 34-43, N-acetyl-, methyl ester; H-Ac-Val-Val-Ser-His-Phe-Asn-Asp-Lys-Tyr-Cys-OMe; CAS 97474-87-8; TGF-α (34-43) peptide derivative
EINECS	Contact for details

Quality Control

Every batch of n-Acetyl-Transforming Growth Factor-A Fragment 34-43 Methyl Ester Human is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with high-purity research standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and peptide content is provided with each shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.