Description

Cyclo(Valyl-Prolylglycyl)4 is a synthetic cyclic tetrapeptide derivative, specifically a repeating sequence of valine, proline, and glycine. This compound is valued for its structural rigidity and potential as a scaffold in advanced pharmaceutical research and peptide-based drug discovery. It serves as a critical intermediate or reference standard for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors, particularly those focused on developing novel therapeutics and diagnostic agents.

Application

• Pharmaceutical Research & Development: Used as a key intermediate or building block in the synthesis of novel peptide-based drugs and therapeutic agents.
• Biochemical Research: Serves as a model compound or reference standard for studying peptide conformation, stability, and biological activity.
• Drug Discovery Scaffold: Its cyclic structure provides a constrained framework for designing and optimizing new drug candidates with improved metabolic stability and target specificity.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for fundamental studies in medicinal chemistry and peptide science.
• Diagnostic Reagent Development: Potential use in the development of specialized diagnostic kits and assays that require specific peptide sequences.
• Cosmeceutical Ingredient Research: Investigated for potential applications in advanced skincare formulations targeting specific biological pathways.

Basic Information

Product Name	Cyclo(Valyl-Prolylglycyl)4
CAS No.	97458-79-2
Molecular Formula	C44H64N12O12
Molecular Weight	929.06 g/mol
Synonyms	Cyclo(-Val-Pro-Gly-)4; Cyclo(VPG)4; Cyclic (Val-Pro-Gly)4 Tetrapeptide; Cyclo(L-Valyl-L-prolylglycyl)4; 4-Val-Pro-Gly Cyclic Tetramer; Cyclotetrapeptide (VPG)4; Cyclo[Val-Pro-Gly]4; (VPG)4 Cyclic Peptide
EINECS	Contact for details

Quality Control

Our Cyclo(Valyl-Prolylglycyl)4 is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Quality is verified through advanced analytical techniques including HPLC, MS, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and related substances is provided with each shipment. We support compliance with relevant cGMP and ISO guidelines for laboratory and pre-clinical materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.