Description

Proline, 5-Methyl-, Methyl Ester, cis- (9Ci) is a specialized proline derivative, a key chiral building block in organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of pharmaceuticals and bioactive peptides. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications requiring high stereochemical purity.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly protease inhibitors and other bioactive molecules.
• Peptidomimetics Research: Used in the design and synthesis of peptide analogs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a building block for creating advanced, stereospecific pesticides and herbicides.
• Asymmetric Catalysis: Can be utilized as a precursor for chiral ligands or catalysts in enantioselective reactions.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	Proline, 5-Methyl-, Methyl Ester, cis- (9Ci)
CAS No.	97373-38-1
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	cis-5-Methyl-L-proline methyl ester; Methyl cis-5-methylprolinate; (2S,5S)-5-Methylpyrrolidine-2-carboxylic acid methyl ester; L-Proline, 5-methyl-, methyl ester, cis-; Methyl (2S,5S)-5-methylprolinate; 5-Methylproline methyl ester (cis); cis-5-Methylproline methyl ester
EINECS	Contact for details

Quality Control

Our Proline, 5-Methyl-, Methyl Ester, cis- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.