Description

H-Pro-Phe-Nh2 Hcl is a high-purity dipeptide derivative, specifically the hydrochloride salt of H-Pro-Phe-NH₂. This compound serves as a critical building block (protected amino acid) in solid-phase peptide synthesis (SPPS) and other advanced organic synthesis workflows. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who require reliable, high-quality intermediates for developing novel therapeutic peptides and biochemical tools.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex therapeutic peptides and peptidomimetics.
• Biochemical Research: Used in proteomics and enzymology studies as a substrate or inhibitor analog.
• Solid-Phase Peptide Synthesis (SPPS): A crucial protected amino acid derivative for the sequential assembly of peptide chains.
• Combinatorial Chemistry: Serves as a scaffold or component in the generation of diverse chemical libraries for drug discovery.
• Academic & Industrial R&D: Fundamental reagent for investigating peptide structure-activity relationships (SAR).
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in HPLC and LC-MS.

Basic Information

Product Name	H-Pro-Phe-Nh2 Hcl
CAS No.	97372-02-6
Molecular Formula	C₁₄H₂₀N₃O₃·HCl
Molecular Weight	315.79 g/mol
Synonyms	L-Phenylalanyl-L-prolinamide hydrochloride; Pro-Phe-NH₂·HCl; H-Pro-Phe-NH₂ hydrochloride; N-[(Benzyloxy)carbonyl]-L-phenylalanyl-L-prolinamide hydrochloride (related protected form); L-Prolinamide, L-phenylalanyl-, hydrochloride; Fmoc-Phe-Pro-NH₂ (precursor); Z-Pro-Phe-NH₂ hydrochloride; Peptide synthesis intermediate 97372-02-6
EINECS	Contact for details

Quality Control

Our H-Pro-Phe-Nh2 Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-L isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.2%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.