Description

4-Amino-4-Deoxychorismate is a key biochemical intermediate in the folate biosynthesis pathway. This compound matters significantly for research and development in microbiology and pharmaceutical chemistry, particularly in the study of antibiotic resistance and the development of novel antimicrobial agents. It is primarily needed by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in metabolic pathway analysis and drug discovery.

Application

• Biochemical Research: Critical intermediate for studying the shikimate and folate biosynthesis pathways in bacteria and plants.
• Antimicrobial Development: Used in target-based screening and mechanism-of-action studies for developing new antibiotics that inhibit folate synthesis.
• Enzyme Inhibition Studies: Serves as a substrate or inhibitor for enzymes like 4-amino-4-deoxychorismate lyase, facilitating kinetic and structural studies.
• Metabolic Engineering: A building block in engineered microbial systems for the production of folate derivatives and other high-value compounds.
• Pharmaceutical Reference Standard: Employed as a high-purity analytical standard in quality control and regulatory testing for related pharmaceutical products.
• Academic & Educational Use: Utilized in university laboratories for teaching advanced concepts in enzymology and metabolic biochemistry.

Basic Information

Product Name	4-Amino-4-Deoxychorismate
CAS No.	97279-79-3
Molecular Formula	C14H16N2O7
Molecular Weight	324.29 g/mol
Synonyms	4-Amino-4-deoxychorismic acid; ADC; 4-Amino-4-deoxychorismate; 2-[(1-carboxy-4-amino-4-oxobutyl)amino]-5-[(1-carboxyvinyl)oxy]benzoic acid; 4-Amino-4-deoxychorismate, ADC; 4-Aminochorismate; 4-ADC; 4-Amino-4-deoxychorismate (ADC)
EINECS	Contact for details

Quality Control

Our 4-Amino-4-Deoxychorismate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.