Description

n-ω-Tosyl-D-Arginine is a high-purity, protected derivative of the amino acid D-arginine, specifically designed for advanced peptide synthesis and biochemical research. This compound is critical for researchers and manufacturers requiring precise stereochemical control and side-chain protection in complex molecular assemblies. It is primarily utilized in the pharmaceutical, biotechnology, and life science sectors for the development of novel therapeutic peptides, enzyme inhibitors, and as a key chiral building block.

Application

• Peptide Synthesis: Serves as a crucial protected D-arginine building block in Solid-Phase Peptide Synthesis (SPPS) and solution-phase methods.
• Pharmaceutical Intermediates: Used in the research and development of peptide-based drugs, including hormone analogs and antimicrobial peptides.
• Biochemical Research: Acts as a substrate or inhibitor in enzymatic studies and proteomics research due to its specific arginine side-chain modification.
• Chiral Pool Synthesis: Provides a source of enantiomerically pure D-arginine for the asymmetric synthesis of complex natural products and bioactive molecules.
• Protease Inhibitor Development: Utilized in designing and testing inhibitors for trypsin-like serine proteases, where the arginine moiety is key.
• Standards and References: Employed as an analytical standard in quality control laboratories for peptide and amino acid analysis.

Basic Information

Product Name	n-ω-Tosyl-D-Arginine
CAS No.	97233-92-6
Molecular Formula	C17H28N4O4S
Molecular Weight	384.49 g/mol
Synonyms	D-Arg(Tos)-OH; N(omega)-Tosyl-D-arginine; D-Arginine, N2-[(4-methylphenyl)sulfonyl]-; H-D-Arg(Tos)-OH; (R)-2-Amino-5-[(4-methylphenyl)sulfonyl]guanidino]pentanoic acid; Nω-Tosyl-D-arginine; Tos-D-Arg-OH; Protected D-Arginine derivative
EINECS	Contact for details

Quality Control

Our n-ω-Tosyl-D-Arginine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, optical rotation for chiral integrity, and NMR/IR for structural confirmation. We provide full traceability and Certificates of Analysis (COA) with each shipment, ensuring compliance with research and development standards. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.