Description

4-Chloro-2-(Methylsulfonyl)Pyrimidine is a high-purity, versatile pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a chloro and a methylsulfonyl substituent, makes it a valuable electrophilic intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of chemical probes.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Chloro-2-(Methylsulfonyl)Pyrimidine
CAS No.	97229-11-3
Molecular Formula	C5H5ClN2O2S
Molecular Weight	192.62 g/mol
Synonyms	2-(Methylsulfonyl)-4-chloropyrimidine; 4-Chloro-2-methanesulfonylpyrimidine; 4-Chloro-2-methylsulfonylpyrimidine; Pyrimidine, 4-chloro-2-(methylsulfonyl)-; 97229-11-3; 4-Chloro-2-(methylsulphonyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(Methylsulfonyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming it meets the agreed specifications for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.