Description

L-Proline 2-Naphthylamide Hydrobromide is a specialized chiral building block and biochemical reagent of significant interest in advanced organic synthesis and pharmaceutical research. Its value lies in its role as a key intermediate for developing enzyme inhibitors and peptidomimetics, particularly targeting proteases. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors engaged in drug discovery and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of protease inhibitors and other therapeutic agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for proline-specific enzymes.
• Peptidomimetic Development: Serves as a core structure for designing and synthesizing novel peptide analogs with enhanced stability and bioavailability.
• Organic Synthesis: A valuable chiral synthon in asymmetric synthesis for constructing complex molecular architectures.
• Diagnostic Reagent Manufacturing: Potential use in developing assay kits and diagnostic tools for clinical research.

Basic Information

Product Name	L-Proline 2-Naphthylamide Hydrobromide
CAS No.	97216-17-6
Molecular Formula	C₁₅H₁₇N₃O • HBr
Molecular Weight	336.23 g/mol
Synonyms	L-Proline-β-naphthylamide hydrobromide; H-Pro-2-Nap-OH • HBr; 2-Naphthylamide of L-Proline Hydrobromide; (S)-1-(2-Naphthamido)pyrrolidine-2-carboxylic Acid Hydrobromide; Proline-2-naphthylamide HBr; L-Pro-2-NA HBr; N-2-Naphthoyl-L-proline Amide Hydrobromide
EINECS	Contact for details

Quality Control

Our L-Proline 2-Naphthylamide Hydrobromide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.