Description

Ammodytoxin A CAS NO 97089-72-0 is a potent phospholipase A2 (PLA2) enzyme isolated from the venom of the nose-horned viper (*Vipera ammodytes ammodytes*). This highly specific biochemical tool is critical for research into phospholipid metabolism, inflammatory pathways, and neurotoxicity mechanisms. It is primarily utilized by pharmaceutical R&D laboratories, academic institutions, and biotechnology companies engaged in enzymology, toxicology, and novel drug discovery.

Application

• Biochemical Research: As a substrate-specific enzyme for studying phospholipase A2 activity, kinetics, and inhibition in model systems.
• Toxinology & Venom Studies: For the analysis of venom composition, mechanism of action, and the development of targeted antivenoms.
• Inflammation & Signal Transduction Research: To investigate the role of secreted PLA2s in inflammatory cascades, eicosanoid production, and cell signaling pathways.
• Drug Discovery Screening: Used in high-throughput assays to identify and characterize novel PLA2 inhibitors for therapeutic development.
• Neuroscience Research: For studying presynaptic neurotoxicity and its effects on neurotransmitter release.
• Reference Standard: Serves as a purified standard for quality control and analytical method development in related biochemical preparations.

Basic Information

Product Name	Ammodytoxin A
CAS No.	97089-72-0
Molecular Formula	C₁₃₈₀H₂₁₀₈N₃₈₈O₄₂₀S₄₀ (Approx., based on PLA2 class)
Molecular Weight	~15-16 kDa (Approximate)
Synonyms	Vipera ammodytes ammodytes phospholipase A2; Ammodytoxin; Ammodytoxin A1; PLA2 Ammodytoxin A; Vipera ammodytes ammodytes toxin; Presynaptic neurotoxin; Secretory phospholipase A2 (sPLA2) from Vipera ammodytes; VaaPLA2
EINECS	Contact for details

Quality Control

Our Ammodytoxin A is produced and purified under stringent conditions to ensure high biological activity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including activity assays, purity assessment, and identity confirmation. A detailed Certificate of Analysis (COA) documenting purity (typically >95% by HPLC), specific activity, and endotoxin levels is provided with every shipment to support your research compliance.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized powder at -20°C or below. Reconstituted solutions should be aliquoted and stored at -70°C or below to prevent loss of activity. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (HPLC)	≥ 95%
Specific Activity	≥ 150 units/mg protein (Contact for exact value)
Protein Content (Biuret)	≥ 90%
Endotoxin Level (LAL)	< 1.0 EU/μg
Solubility	Soluble in water or appropriate buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.