Description

8-Bromo-7-[2-(4-Ethylphenyl)-2-Oxo-Ethyl]-1,3-Dimethyl-Purine-2,6-Dion E is a high-purity xanthine derivative, specifically a 7-benzyl-substituted theophylline analog, valued as a critical pharmaceutical intermediate and research chemical. This compound is essential for the synthesis of advanced drug candidates, particularly those targeting adenosine receptors and related neurological pathways. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and pharmacology.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel adenosine receptor antagonists and other purine-based therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new compounds for central nervous system (CNS) disorders.
• Biochemical Tool Compound: Serves as a selective ligand in pharmacological assays to study adenosine A1, A2A, and A2B receptor subtypes.
• Preclinical Development: Employed in the production of active pharmaceutical ingredients (APIs) for early-stage drug development and toxicity studies.
• Academic Research: Utilized in university and institutional labs for fundamental research on purinergic signaling and its role in inflammation, ischemia, and neurodegeneration.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	8-Bromo-7-[2-(4-Ethylphenyl)-2-Oxo-Ethyl]-1,3-Dimethyl-Purine-2,6-Dion E
CAS No.	96885-28-8
Molecular Formula	C₁₇H₁₇BrN₄O₃
Molecular Weight	405.25 g/mol
Synonyms	8-Bromo-1,3-dimethyl-7-[2-(4-ethylphenyl)-2-oxoethyl]-3,7-dihydro-1H-purine-2,6-dione; 8-Bromo-7-(2-(4-ethylbenzoyl)ethyl)-1,3-dimethylxanthine; 8-Bromo-1,3-dimethyl-7-(2-(4-ethylphenyl)-2-oxoethyl)xanthine; 8-Br-1,3-DM-7-BPET; 8-Bromo-7-(4-ethylphenacyl)-1,3-dimethylxanthine; Adenosine receptor ligand intermediate; Xanthine derivative 96885-28-8
EINECS	Contact for details

Quality Control

Our production of 8-Bromo-7-[2-(4-Ethylphenyl)-2-Oxo-Ethyl]-1,3-Dimethyl-Purine-2,6-Dion E adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry. We provide detailed Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our commitment to cGMP principles guarantees batch-to-batch consistency for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed in a dry environment to prevent moisture uptake. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.