Description

2,4-Dichloro-5-Fluoro-6-Trifluoromethyl-Pyrimidine is a high-value, multi-halogenated pyrimidine building block essential for advanced organic synthesis. Its unique structure, featuring chlorine, fluorine, and a trifluoromethyl group, makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel antiviral, anticancer, and antibacterial agents, leveraging its halogenated pyrimidine core.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for specialty polymers, liquid crystals, and electronic materials requiring specific fluorinated aromatic components.
• Custom Synthesis & Contract Manufacturing: Employed in research-scale and pilot-scale projects for creating bespoke chemical entities (BCEs) and active pharmaceutical ingredients (APIs).
• Fluorine Chemistry Research: A valuable reagent for studying nucleophilic aromatic substitution (SNAr) reactions and introducing fluorinated motifs into complex molecular architectures.

Basic Information

Product Name	2,4-Dichloro-5-Fluoro-6-Trifluoromethyl-Pyrimidine
CAS No.	96819-53-3
Molecular Formula	C5HCl2F4N2
Molecular Weight	232.97 g/mol
Synonyms	5-Fluoro-2,4-dichloro-6-(trifluoromethyl)pyrimidine; 2,4-Dichloro-5-fluoro-6-(trifluoromethyl)pyrimidine; 6-(Trifluoromethyl)-2,4-dichloro-5-fluoropyrimidine; 96819-53-3; Pyrimidine, 2,4-dichloro-5-fluoro-6-(trifluoromethyl)-; 2,4-Dichloro-5-fluoro-6-trifluoromethylpyrimidine
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-5-Fluoro-6-Trifluoromethyl-Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.