Description

Cardionatrin Iii is a synthetic peptide of significant interest in cardiovascular and renal research. This compound, identified by CAS No. 96725-56-3, serves as a crucial tool for investigating natriuretic peptide pathways and their physiological effects. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on developing novel therapeutic agents for conditions like hypertension and heart failure.

Application

• Pharmaceutical Research & Development: A key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel cardiovascular drugs.
• Biochemical Assay Development: Used as a critical reagent in the development and validation of high-throughput screening (HTS) assays for natriuretic peptide receptors.
• Mechanistic Studies: Employed in preclinical research to study the vasodilatory, diuretic, and natriuretic effects of atrial natriuretic peptide (ANP) analogs.
• Standards & Calibration: Serves as a certified reference material (CRM) for quantitative analysis in bioanalytical methods such as LC-MS/MS and ELISA.
• Academic Research: Used in university and institutional labs to explore the role of natriuretic peptides in blood pressure regulation and fluid homeostasis.

Basic Information

Product Name	Cardionatrin Iii
CAS No.	96725-56-3
Molecular Formula	C145H244N50O43S2
Molecular Weight	~3280.9 g/mol
Synonyms	Atrial Natriuretic Peptide (ANP) (5-28); ANP (5-28); Atriopeptin III; Cardionatrin III; Auriculin B; rANP (5-28); H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH (Disulfide bridge: Cys7-Cys23)
EINECS	Contact for details

Quality Control

Our Cardionatrin Iii is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by AAA)
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.