Description

β-Endorphin, 2-Nitro-4-Azidophenylsulfenyl- CAS NO 96725-48-3 is a chemically modified derivative of the endogenous opioid peptide β-endorphin, designed as a specialized biochemical tool for advanced research. This derivative is critical for studies involving photoaffinity labeling, receptor mapping, and the elucidation of complex neurobiological pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on neuroscience, pain management, and opioid receptor pharmacology.

Application

• Photoaffinity Labeling Studies: Acts as a covalent cross-linking agent to identify and characterize opioid receptor binding sites.
• Neurobiological Research: Used in fundamental research to study the structure, function, and signaling mechanisms of endogenous opioid systems.
• Drug Discovery & Development: Serves as a key intermediate or probe in the design and screening of novel analgesic and neurotherapeutic compounds.
• Biochemical Assay Development: Employed in the development of specialized in vitro assays for receptor-ligand interaction analysis.
• Proteomics and Molecular Mapping: Facilitates the identification of peptide-protein interactions within complex biological matrices.

Basic Information

Product Name	β-Endorphin, 2-Nitro-4-Azidophenylsulfenyl- CAS NO 96725-48-3
CAS No.	96725-48-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2-Nitro-4-azidophenylsulfenyl β-Endorphin; NAPS-β-Endorphin; β-Endorphin NAPS derivative; Photoactivatable β-Endorphin; β-Endorphin (2-Nitro-4-azidophenylsulfenyl); Opioid Peptide Photoaffinity Label; CAS 96725-48-3
EINECS	Contact for details

Quality Control

Our β-Endorphin, 2-Nitro-4-Azidophenylsulfenyl- is produced under stringent conditions suitable for research applications. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and MS for identity confirmation, to ensure consistent quality and performance. Certificates of Analysis (COA) detailing purity, identity, and other critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, the product should be handled under anhydrous conditions and allowed to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.