Description

Heme A is a critical prosthetic group and a vital biochemical cofactor essential for cellular respiration. Its primary commercial value lies in its role as the active center of cytochrome c oxidase, the terminal enzyme in the mitochondrial electron transport chain. This makes it a key compound for research in biochemistry, enzymology, and the development of bio-inspired catalysts. Industries requiring this high-purity biochemical include pharmaceutical research, diagnostic reagent manufacturing, and advanced materials science.

Application

• Biochemical Research & Enzymology: Essential for studying the structure, function, and mechanism of cytochrome c oxidase and other heme-containing enzymes.
• Pharmaceutical Development: Used as a reference standard and an intermediate in research targeting mitochondrial function, metabolic disorders, and oxidative stress.
• Diagnostic Reagents: Serves as a critical component in the development of specialized assays and biosensors for clinical diagnostics.
• Bio-Inspired Catalysis: Investigated as a model compound for designing novel catalysts that mimic the efficiency of natural enzymatic systems.
• Nutritional & Cosmetic Research: Explored in high-end research for its potential bioactivity, though applications are strictly investigational.

Basic Information

Product Name	Heme A
CAS No.	18535-39-2
Molecular Formula	C49H56FeN4O6
Molecular Weight	852.85 g/mol
Synonyms	Heme A; Cytochrome a Heme; Heme of Cytochrome c Oxidase; Iron, [7-(2-hydroxy-3,5,9,13-tetramethyl-10-oxo-4,8,14,17-tetraoxa-3,9,13-triazaheptadec-16-en-1-yl)-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(2-)-κN21,κN22,κN23,κN24]-, (SP-5-13)-; Ferroheme a; Protoheme IX
EINECS	Contact for details

Quality Control

Our Heme A is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and related substances is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	Dark brown to black solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in DMSO, alkaline aqueous solutions
Loss on Drying	≤ 2.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.