Description

Hemoglobin F-Clarke is a specialized biochemical reagent of high purity, primarily used as a critical standard and reference material in clinical diagnostics and hematological research. Its precise and consistent composition is essential for the accurate calibration of analytical instruments and the validation of testing methodologies. This product is vital for research institutions, clinical laboratories, and diagnostic kit manufacturers focused on fetal hemoglobin analysis and related blood disorders.

Application

• Primary standard for the quantification of Hemoglobin F (HbF) in clinical diagnostic assays.
• Critical reference material for calibrating HPLC, electrophoresis, and immunoassay systems used in hemoglobinopathy screening.
• Essential component in the development and quality control of diagnostic kits for sickle cell disease and β-thalassemia.
• Used in hematological research to study fetal hemoglobin expression, regulation, and its role in genetic disorders.
• Acts as a control material in proficiency testing programs for clinical laboratories to ensure testing accuracy.
• Biochemical reagent for method validation and standardization studies in accordance with CLSI and other regulatory guidelines.

Basic Information

Product Name	Hemoglobin F-Clarke
CAS No.	112444-76-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hb F-Clarke; Hemoglobin F Clarke Variant; Fetal Hemoglobin Clarke; HbF Clarke; Clarke Hemoglobin F; γ-Globin Variant Clarke; Hemoglobin F (Clarke); Glycosylated Hemoglobin F Standard
EINECS	Contact for details

Quality Control

Our Hemoglobin F-Clarke is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and reliability for critical diagnostic applications. Each lot undergoes comprehensive analytical testing, including purity assessment by HPLC and identity confirmation. A Certificate of Analysis (COA) detailing all test results is provided to guarantee compliance with specified standards for research and diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at 2-8°C. Avoid repeated freeze-thaw cycles. Handle as a moisture-sensitive material.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (HPLC)	Conforms to standard
Purity (HPLC)	≥ 95%
Solubility	Clear solution in specified buffer
Protein Content (BCA)	Reported on COA
Hemoglobin F Content	Reported on COA
Endotoxin	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.